| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CYP11B2 |
| Specificity: |
This antibody reacts specifically with CYP11B2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CYP11B2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Jul 2008], Mutations in this gene cause corticosterone methyl oxidase deficiency, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity, This protein localizes to the mitochondrial inner membrane, [provided by RefSeq, steroids and other lipids, This gene encodes a member of the cytochrome P450 superfamily of enzymes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CYP11BL CPN2 P-450C18 P450aldo ALDOS |
| Also known as: |
CYP11B2 Polyclonal Antibody |
| Other name: |
Anti-CYP11B2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CYP11B2 |
| Short name: |
Anti-CYP11B2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CYP11B2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2592 |
| Gene: |
CYP11B2 |
More about : CYP11B2 |
| Long gene name: |
cytochrome P450 family 11 subfamily B member 2 |
| Synonyms gene: |
CYP11B |
| Synonyms gene name: |
cytochrome P450, family 11, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily B, subfamily XIB (steroid 11-beta-hydroxylase) |
| Synonyms name: |
steroid 11-beta-monooxygenase |
| Locus: |
8q24, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X54741 |
| Entrez gene record: |
1585 |
| Pubmed identfication: |
1303253 |
| Classification: |
Cytochrome P450 family 11 |
| Havana BLAST/BLAT: |
OTTHUMG00000160254 |