| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDZ RHOGEF/GTRAP48 |
| Specificity: |
This antibody reacts specifically with PDZ RHOGEF/GTRAP48 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity, Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia, Jul 2008], The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals, Two alternative transcripts encoding different isoforms have been described, [provided by RefSeq, Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0380 GTRAP48 PDZ-RHOGEF |
| Also known as: |
PDZ RHOGEF/GTRAP48 Polyclonal Antibody |
| Other name: |
Anti-PDZ RHOGEF/GTRAP48 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PDZ RHOGEF/GTRAP48 |
| Short name: |
Anti-PDZ RHOGEF/GTRAP48 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PDZ RHOGEF/GTRAP48 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14580 |
| Gene: |
ARHGEF11 |
More about : ARHGEF11 |
| Long gene name: |
Rho guanine nucleotide exchange factor 11 |
| Synonyms gene name: |
Rho guanine nucleotide exchange factor (GEF) 11 |
| Locus: |
1q23, 1 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AB002378 |
| Entrez gene record: |
9826 |
| Pubmed identfication: |
10526156 9205841 |
| RefSeq identity: |
NM_198236 |
| Classification: |
Rho guanine nucleotide exchange factors PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000041292 |