| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ZFAND5 |
| Specificity: |
This antibody reacts specifically with ZFAND5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ZFAND5 |
| Gene ID: |
7763 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Could be involved in regulating NF-kappa-B activation and apoptosis, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner, Inhibits also tumor necrosis (TNF), Involved in protein degradation via the ubiquitin-proteasome system and plays a critical role in muscle atrophy, Is a potent inhibitory factor for osteoclast differentiation, May act by anchoring ubiquitinylated proteins to the proteasome, Overexpression sensitizes cells to TNF-induced apoptosis, playing a critical role in protein degradation, Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ZFAND5A |
| Also known as: |
ZFAND5 Polyclonal Antibody |
| Other name: |
Anti-ZFAND5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ZFAND5 |
| Short name: |
Anti-ZFAND5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, AN1-classification domain 5 (polyclonal), antibody to-zinc finger |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AN1-type domain 5, Cytoplasm, ZA20D2 and ZFAND5A and ZNF216, ZFAND5 and IDBG-632244 and ENSBTAG00000009417 and 404110, ZFAND5 and IDBG-70778 and ENSG00000107372 and 7763, Zfand5 and IDBG-152381 and ENSMUSG00000024750 and 22682, this GO :0001701 and in utero embryonic development and biological process this GO :0001944 and vasculature development and biological process this GO :0003016 and respiratory system process and biological process this GO :0003674 and molecular function and molecular function this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008150 and biological process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010761 and fibroblast migration and biological process this GO :0048008 and platelet-derived growth factor receptor signaling pathway and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0060324 and face development and biological process, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding, this GO :0003677 : DNA binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, zinc ion binding, zinc finger |
| Identity: |
13008 |
| Gene: |
ZFAND5 |
More about : ZFAND5 |
| Long gene name: |
zinc finger AN1-type containing 5 |
| Synonyms gene: |
ZNF216 ZA20D2 |
| Synonyms gene name: |
A20 domain containing 2 zinc finger, AN1-type domain 5 , zinc finger protein 216 zinc finger |
| Locus: |
9q21, 13 |
| Discovery year: |
1998-04-20 |
| GenBank acession: |
AF062072 |
| Entrez gene record: |
7763 |
| Pubmed identfication: |
9758550 |
| Classification: |
Zinc fingers AN1-type |
| Havana BLAST/BLAT: |
OTTHUMG00000020008 |