| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DR4 / Death Receptor 4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the DR4 antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00220 |
| Purity: |
Antigen affinity |
| Description: |
DR4 or TRAILR1, Studies with FADD-deficient mice suggested that FADD, The protein encoded by this gene is a member of the TNF-receptor superfamily, This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), a death domain containing adaptor protein, also known as APO2, and thus transduces cell death signal and induces cell apoptosis, is a protein that in humans is encoded by the TNFRSF10A gene, is required for the apoptosis mediated by this protein, TNFRSF10A (Tumor Necrosis Factor Receptor Subfamily Member 10A) |
| Immunogen: |
Amino acids 99-131 (VLLQVVPSSAATIKLHDQSIGTQQWEHSPLGEL-human) were used as the immunogen for the DR4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DR4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DR4 / Death Receptor 4 |
| Short name: |
DR4 Antibody / Death Receptor 4 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DR4 (Antibody to) / Death Receptor 4 |
| Alternative technique: |
antibodies |
| Identity: |
11904 |
| Gene: |
TNFRSF10A |
More about : TNFRSF10A |
| Long gene name: |
TNF receptor superfamily member 10a |
| Synonyms gene name: |
member 10a , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR4 Apo2 TRAILR-1 CD261 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U90875 |
| Entrez gene record: |
8797 |
| Pubmed identfication: |
9311998 9082980 |
| RefSeq identity: |
NM_003844 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097843 |