| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SLC7A5 |
| Specificity: |
This antibody reacts specifically with SLC7A5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Transmembrane, Helical |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLC7A5 |
| Gene ID: |
8140 |
| Swiss Prot: |
Q01650 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as an amino acid exchanger, Acts as the major transporter of tyrosine in fibroblasts, Involved in cellular amino acid uptake, Involved in the cellular activity of small molecular weight nitrosothiols, Involved in the transport of L-DOPA across the blood-brain barrier, Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D, May play an important role in high-grade gliomas, Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina, Plays a role in neuronal cell proliferation (neurogenesis) in brain, and hence plays a role in metal ion homeostasis and toxicity, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta, arginine and tryptophan, high-affinity transport of large neutral amino acids such as phenylalanine, leucine, tyrosine, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane, when associated with SLC3A2/4F2hc, L-homocysteine complexes, Sodium-independent |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAT1 E16 D16S469E MPE16 CD98 |
| Also known as: |
SLC7A5 Polyclonal Antibody |
| Other name: |
Anti-SLC7A5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SLC7A5 |
| Short name: |
Anti-SLC7A5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SLC7A5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11063 |
| Gene: |
SLC7A5 |
More about : SLC7A5 |
| Long gene name: |
solute carrier family 7 member 5 |
| Synonyms gene name: |
L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Locus: |
16q24, 2 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
AF077866 |
| Entrez gene record: |
8140 |
| Pubmed identfication: |
9751058 7829099 |
| RefSeq identity: |
NM_003486 |
| Classification: |
Solute carriers CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137658 |