| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
gp130 Ser782 |
| Specificity: |
This antibody reacts specifically with gp130 (Ser782) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser782 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human gp130 around the phosphorylation site of Ser782 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding distinct isoforms have been described, Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis, The activation of this protein is dependent upon the binding of cytokines to their receptors, This protein functions as a part of the cytokine receptor complex, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, and oncostatin M (OSM), can bypass the interleukin 6 receptor (IL6R) and directly activate this protein, ciliary neurotrophic factor (CNTF), including interleukin 6 (IL6), leukemia inhibitory factor (LIF), vIL6, CD130 is a signal transducer shared by many cytokines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD130, CD_antigen, CDw130, GP130 RAPS, GP130-RAPS, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, IL6 ST, IL6R-beta, IL6RB_HUMAN, IL6ST, Interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, gp130, gp130 phospho Ser782, gp130 transducer chain, p-gp130 Ser782, IL6R-beta, gp130 phospho S782 |
| Also known as: |
gp130 (Ser782) Polyclonal Antibody |
| Other name: |
Anti-gp130 (Ser782) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
gp130 (Ser782) |
| Short name: |
Anti-gp130 (Ser782) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-gp130 (Ser782) (polyclonal) |
| Alternative technique: |
polyclonals |