| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IKK gamma / NEMO |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the IKKG antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y6K9 |
| Purity: |
Antigen affinity |
| Description: |
A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome, Mutations in this gene result in incontinentia pigmenti, This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK<, and other pathways, and several other types of immunodeficiencies, cell survival, hypohidrotic ectodermal dysplasia, immunity, is a protein that in humans is encoded by the IKBKG gene, which activates NF-kappaB resulting in activation of genes involved in inflammation, ), /font>, NF-kappa-B essential modulator (NEMO), font face=symbol>, g< |
| Immunogen: |
Amino acids 207-246 (QSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIK-human) were used as the immunogen for the IKKG antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IKKG antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IKK gamma / NEMO |
| Short name: |
IKK gamma Antibody / NEMO |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IKK g (Antibody to) / NEMO |
| Alternative technique: |
antibodies |
| Identity: |
5961 |
| Gene: |
IKBKG |
More about : IKBKG |
| Long gene name: |
inhibitor of nuclear factor kappa B kinase subunit gamma |
| Synonyms gene: |
IP2 IP1 |
| Synonyms gene name: |
incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| Synonyms: |
IKK-gamma NEMO Fip3p FIP-3 FIP3 ZC2HC9 |
| Locus: |
Xq28 |
| Discovery year: |
1998-09-30 |
| GenBank acession: |
AF074382 |
| Entrez gene record: |
8517 |
| Pubmed identfication: |
9751060 10087442 11590134 |
| RefSeq identity: |
NM_003639 |
| Classification: |
Zinc fingers C2HC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000024234 |
| Locus Specific Databases: |
IKBKGbase: Mutation registry for Nemo deficiency Mental Retardation database LRG_70 |