| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HSP90 alpha |
| Specificity: |
This antibody reacts specifically with HSP90 alpha |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HSP90 alpha |
| Gene ID: |
3320 |
| Swiss Prot: |
P07900 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ATPase cycle and chaperone function, Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, Interacts dynamically with various co-chaperones that modulate its substrate recognition, This cycle probably induces conformational changes in the client proteins, Undergoes a functional cycle that is linked to its ATPase activity, including TNF secretion by monocytes, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction, thereby causing their activation, Molecular chaperone that promotes the maturation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Hsp89 Hsp90 FLJ31884 HSP90N |
| Also known as: |
HSP90 alpha Polyclonal Antibody |
| Other name: |
Anti-HSP90 alpha Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HSP90 alpha |
| Short name: |
Anti-HSP90 alpha (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HSP90 a (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5253 |
| Gene: |
HSP90AA1 |
More about : HSP90AA1 |
| Long gene name: |
heat shock protein 90 alpha family class A member 1 |
| Synonyms gene: |
HSPC1 HSPCA |
| Synonyms gene name: |
alpha heat shock 90kDa protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 , heat shock 90kD protein 1 |
| Locus: |
14q32, 31 |
| Discovery year: |
1990-06-27 |
| GenBank acession: |
M27024 |
| Entrez gene record: |
3320 |
| Pubmed identfication: |
2527334 16269234 |
| RefSeq identity: |
NM_005348 |
| Classification: |
Heat shock 90kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171752 |