| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD11b / MAC-1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the mouse CD11b antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05555 |
| Purity: |
Antigen affinity |
| Description: |
ITGAM probably recognizes the R-G-D peptide in C3b, ITGAM/CD11b has a role in vascular repair after mechanical arterial injury, It is implicated in various adhesive interactions of monocytes, It is mapped to 16p11, What's more, also known as macrophage-1 antigen (Mac-1) or cluster of differentiation molecule 11b (CD11b), and it is also a receptor for fibrinogen, factor X and ICAM1, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles, 2, Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (aM/b2) molecule |
| Immunogen: |
A mouse recombinant protein corresponding to amino acids E260-T360 was used as the immunogen for the mouse CD11b antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the mouse CD11b antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD11b / MAC-1 |
| Short name: |
CD11b Antibody / MAC-1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD11b (Antibody to) / MAC-1 |
| Alternative technique: |
antibodies |
| Identity: |
6149 |
| Gene: |
ITGAM |
More about : ITGAM |
| Long gene name: |
integrin subunit alpha M |
| Synonyms gene: |
CR3A CD11B |
| Synonyms gene name: |
alpha, alpha M (complement component 3 receptor 3 subunit) , alpha M (complement component receptor 3, also known as CD11b (p170), integrin, macrophage antigen alpha polypeptide) integrin |
| Synonyms: |
MAC-1 CD11b |
| Synonyms name: |
complement component 3 receptor 3 subunit |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-05 |
| GenBank acession: |
J03925 |
| Entrez gene record: |
3684 |
| RefSeq identity: |
NM_000632 |
| Classification: |
Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000176612 |