| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GYPB |
| Specificity: |
This antibody reacts specifically with Glycophorin B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Glycophorin B |
| Gene ID: |
2994 |
| Swiss Prot: |
P06028 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
B and C are sialoglycoproteins of the human erythrocyte membrane, Glycophorin C transcript can generate two protein isoforms, Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte, Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein, Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, Ss and Gerbich blood groups, The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual, The human Glycophorin A gene maps to chromosome 4q31, The human Glycophorin B gene maps to chromosome 4q31, The human Glycophorin C gene maps to chromosome 2q14, and encodes a 150 amino acid protein, contains seven exons which are 97% homologous to Glycophorin B, respectively, which bear the antigenic determinants for the MN, which specifies the Yus subtype of the Gerbich phenotype, 21, 21 and encodes a 91 amino acid protein, 3 and contains four exons, Glycophorins A |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GPB SS CD235b |
| Also known as: |
Glycophorin B Polyclonal Antibody |
| Other name: |
Anti-Glycophorin B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Glycophorin B |
| Short name: |
Anti-Glycophorin B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Glycophorin B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4703 |
| Gene: |
GYPB |
More about : GYPB |
| Long gene name: |
glycophorin B (MNS blood group) |
| Synonyms gene: |
MNS |
| Synonyms gene name: |
glycophorin B (includes Ss blood group) glycophorin B (Ss blood group) |
| Locus: |
4q31, 21 |
| Discovery year: |
1988-08-31 |
| Entrez gene record: |
2994 |
| RefSeq identity: |
NM_002100 |
| Classification: |
CD molecules Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000161404 |
| Locus Specific Databases: |
Blood Group Antigen Mutation Database LRG_794 |