| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NFKB p100/p52 |
| Specificity: |
The immunoge used to produce this antibody has 83% sequence similarity with NFKB p105/ p50NFKB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NFKB p52 |
| Gene ID: |
4791 |
| Swiss Prot: |
Q00653 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in multiple transcript variants, Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, Dec 2013], The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function, The p100 full-length protein is co-translationally processed into a p52 active form, The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner, There is a pseudogene for this gene on chromosome 18, [provided by RefSeq, some of which may result in the formation of fusion proteins, This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KBRAS1 kappaB-Ras1 |
| Also known as: |
NFKB Polyclonal Antibody |
| Other name: |
Anti-NFKB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NFKB |
| Short name: |
Anti-NFKB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NFKB (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17899 |
| Gene: |
NKIRAS1 |
More about : NKIRAS1 |
| Long gene name: |
NFKB inhibitor interacting Ras like 1 |
| Synonyms gene name: |
NFKB inhibitor interacting Ras-like protein 1 |
| Locus: |
3p24, 2 |
| Discovery year: |
2004-03-31 |
| GenBank acession: |
AF229839 |
| Entrez gene record: |
28512 |
| Pubmed identfication: |
10657303 |
| RefSeq identity: |
NM_020345 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000155605 |