| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CBX5 Tyr37 |
| Specificity: |
This antibody reacts specifically with CBX5 (Tyr37) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr37 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37 |
| Gene ID: |
23468 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Multiple alternatively spliced variants, The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins, The gene has a pseudogene located on chromosome 3, The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, The protein is enriched in the heterochromatin and associated with centromeres, [provided by RefSeq], and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins, encoding the same protein, have been identified, which is a member of the heterochromatin protein family, This gene encodes a highly conserved nonhistone protein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HP1Hs-alpha HP1 HP1-ALPHA |
| Also known as: |
CBX5 (Tyr37) Polyclonal Antibody |
| Other name: |
Anti-CBX5 (Tyr37) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CBX5 (Tyr37) |
| Short name: |
Anti-CBX5 (Tyr37) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CBX5 (Tyr37) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1555 |
| Gene: |
CBX5 |
More about : CBX5 |
| Long gene name: |
chromobox 5 |
| Synonyms gene name: |
Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog |
| Synonyms name: |
HP1 alpha homolog (Drosophila) |
| Locus: |
12q13, 13 |
| Discovery year: |
1999-10-12 |
| GenBank acession: |
U26311 |
| Entrez gene record: |
23468 |
| Pubmed identfication: |
8663349 |
| RefSeq identity: |
NM_012117 |
| Classification: |
Chromobox family |
| Havana BLAST/BLAT: |
OTTHUMG00000169700 |