| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
VCAM1 |
| Specificity: |
This antibody reacts specifically with VCAM1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human VCAM-1 |
| Gene ID: |
7412 |
| Swiss Prot: |
P19320 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rabbit, Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Appears to function in leukocyte-endothelial cell adhesion, Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation, and mediates both adhesion and signal transduction, Important in cell-cell recognition |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD106 |
| Also known as: |
VCAM1 Polyclonal Antibody |
| Other name: |
Anti-VCAM1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
VCAM1 |
| Short name: |
Anti-VCAM1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-vascular cellular adhesion molecule 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD106 and INCAM-100, Extracellular, VCAM1 and IDBG-100525 and ENSG00000162692 and 7412, Vcam1 and IDBG-189855 and ENSMUSG00000027962 and 22329, cell adhesion molecule binding, this GO :0001666 and response to hypoxia and biological process this GO :0002102 and podosome and cellular component this GO :0002526 and acute inflammatory response and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005902 and microvillus and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007507 and heart development and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0008131 and primary amine oxidase activity and molecular function this GO :0009308 and amine metabolic process and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010043 and response to zinc ion and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022614 and membrane to membrane docking and biological process this GO :0030175 and filopodium and cellular component this GO :0030183 and B cell differentiation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0035094 and response to nicotine and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0045177 and apical part of cell and cellular component this GO :0045471 and response to ethanol and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060669 and embryonic placenta morphogenesis and biological process this GO :0060710 and chorio-allantoic fusion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071065 and alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex and cellular component this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071944 and cell periphery and cellular component, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008131 : primary amine oxidase activity and also this GO :0050839 : cell adhesion molecule binding, this GO :0005515 : protein binding, this GO :0008131 : primary amine oxidase activity, this GO :0050839 : cell adhesion molecule binding, vascular cell adhesion molecule 1 |
| Identity: |
12663 |
| Gene: |
VCAM1 |
More about : VCAM1 |
| Long gene name: |
vascular cell adhesion molecule 1 |
| Locus: |
1p21, 2 |
| Discovery year: |
1991-07-10 |
| GenBank acession: |
M60335 |
| Entrez gene record: |
7412 |
| RefSeq identity: |
NM_001078 |
| Classification: |
Endogenous ligands C2-set domain containing I-set domain containing CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000010982 |