| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ACL / ATP Citrate Lyase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, IHC (FFPE): 1-2ug/ml, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This ATP Citrate Lyase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P53396 |
| Purity: |
Antigen affinity |
| Description: |
ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites, ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine, In nervous tissue, In plants, It is activated by insulin, The enzyme is a tetramer of apparently identical subunits, The product, acetyl-CoA, aslo known as ACLY, in animals serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis, is an enzyme that in animals represents an important step in fatty acid biosynthesis, ATP citrate lyase |
| Immunogen: |
Amino acids M1-I180 from the human protein were used as the immunogen for the ATP Citrate Lyase antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ATP Citrate Lyase antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ACL / ATP Citrate Lyase |
| Short name: |
ACL Antibody / ATP Citrate Lyase |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ACL (Antibody to) / adenosine triphosphate Citrate Lyase |
| Alternative technique: |
antibodies |
| Identity: |
115 |
| Gene: |
ACLY |
More about : ACLY |
| Long gene name: |
ATP citrate lyase |
| Synonyms: |
ATPCL CLATP ACL |
| Synonyms name: |
ATP citrate synthase |
| Locus: |
17q21, 2 |
| Discovery year: |
1994-04-08 |
| GenBank acession: |
X64330 |
| Entrez gene record: |
47 |
| Pubmed identfication: |
1371749 8088842 |
| RefSeq identity: |
NM_001096 |
| Havana BLAST/BLAT: |
OTTHUMG00000133507 |