| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CX3CL1 |
| Specificity: |
This antibody reacts specifically with CX3CL1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CX3CL1 |
| Gene ID: |
6376 |
| Swiss Prot: |
P78423 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds to CX3CR1, May play a role in regulating leukocyte adhesion and migration processes at the endothelium, The membrane-bound form promotes adhesion of those leukocytes to endothelial cells, but not for neutrophils, The soluble form is chemotactic for T-cells and monocytes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NTN C3Xkine ABCD-3 CXC3C CXC3 fractalkine neurotactin |
| Also known as: |
CX3CL1 Polyclonal Antibody |
| Other name: |
Anti-CX3CL1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CX3CL1 |
| Short name: |
Anti-CX3CL1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-chemokine (C-X3-C motif) ligand 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ABCD-3 and C3Xkine and CXC3 and CXC3C and fractalkine and neurotactin and NTN and NTT and SCYD1, CX3CL1 and IDBG-33205 and ENSG00000006210 and 6376, CX3CL1 and IDBG-632469 and ENSBTAG00000024869 and, Cx3cl1 and IDBG-182616 and ENSMUSG00000031778 and 20312, Extracellular, chemokine activity, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006952 and defense response and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0008009 and chemokine activity and molecular function this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030595 and leukocyte chemotaxis and biological process this GO :0032914 and positive regulation of transforming growth factor beta1 production and biological process this GO :0042060 and wound healing and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048246 and macrophage chemotaxis and biological process this GO :0048247 and lymphocyte chemotaxis and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050902 and leukocyte adhesive activation and biological process this GO :0051041 and positive regulation of calcium-independent cell-cell adhesion and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0060326 and cell chemotaxis and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity, this GO :0005515 : protein binding, this GO :0008009 : chemokine activity, chemokine (C-X3-C motif) ligand 1 |
| Identity: |
10647 |
| Gene: |
CX3CL1 |
More about : CX3CL1 |
| Long gene name: |
C-X3-C motif chemokine ligand 1 |
| Synonyms gene: |
SCYD1 |
| Synonyms gene name: |
member 1 (fractalkine, neurotactin) chemokine (C-X3-C motif) ligand 1 , small inducible cytokine subfamily D (Cys-X3-Cys) |
| Locus: |
16q21 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U84487 |
| Entrez gene record: |
6376 |
| Pubmed identfication: |
9177350 9024663 |
| RefSeq identity: |
NM_002996 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000133469 |