| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Caldesmon / CAD |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the Caldesmon antibody should be determined by the researcher |
| Intented use: |
This Caldesmon antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q05682 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms, It is mapped to 7q33, The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction, This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, actin, and phospholipids, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction, myosin, tropomyosin, Caldesmon is a protein that in humans is encoded by the CALD1 gene |
| Immunogen: |
Amino acids M1-E120 of the human protein were used as the immunogen for the Caldesmon antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Caldesmon antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Caldesmon / CAD |
| Short name: |
Caldesmon / CAD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Caldesmon / CAD (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1424 |
| Gene: |
CAD |
More about : CAD |
| Long gene name: |
and dihydroorotase , aspartate transcarbamylase, carbamoyl-phosphate synthetase 2 |
| Locus: |
2p23, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
D78586 |
| Entrez gene record: |
790 |
| Pubmed identfication: |
8619816 2565865 |
| Havana BLAST/BLAT: |
OTTHUMG00000097070 |