| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
B7H4 |
| Specificity: |
This antibody reacts specifically with B7H4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from Rat B7H4 |
| Gene ID: |
295322 |
| Swiss Prot: |
Q501W4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Involved in promoting epithelial cell transformation (By similarity), When expressed on the cell surface of tumor macrophages, cytokine production and development of cytotoxicity, in the suppression of tumor-associated antigen-specific T-cell immunity, plays an important role, proliferation, together with regulatory T-cells (Treg), Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
B7-H4 FLJ22418 B7S1 B7X B7H4 |
| Also known as: |
B7H4 Polyclonal Antibody |
| Other name: |
Anti-B7H4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
B7H4 |
| Short name: |
Anti-B7H4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-B7H4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
28873 |
| Gene: |
VTCN1 |
More about : VTCN1 |
| Long gene name: |
V-set domain containing T-cell activation inhibitor 1 |
| Synonyms gene name: |
V-set domain containing T cell activation inhibitor 1 |
| Synonyms name: |
B7 family member, H4 B7 superfamily member 1 |
| Locus: |
1p13, 1-p12 |
| Discovery year: |
2005-02-25 |
| GenBank acession: |
BX648021 |
| Entrez gene record: |
79679 |
| Pubmed identfication: |
12818165 12818166 |
| RefSeq identity: |
NM_024626 |
| Classification: |
V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000012118 |