| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DNA polymerase eta / POLH |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the DNA polymerase eta antibody should be determined by the researcher |
| Intented use: |
This DNA polymerase eta antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y253 |
| Purity: |
Antigen affinity |
| Description: |
However, It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases, Mutations in this gene result in XPV, Several transcript variants encoding different isoforms have been found for this gene, This gene encodes a member of the Y family of specialized DNA polymerases, This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination, a variant type of xeroderma pigmentosum, is a protein that in humans is encoded by the POLH gene, it accurately replicates UV-damaged DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, when thymine dimers are present, DNA polymerase eta (POLH) |
| Immunogen: |
Amino acids 157-361 of human POLH were used as the immunogen for the DNA polymerase eta antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DNA polymerase eta antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DNA polymerase eta / POLH |
| Short name: |
DNA polymerase eta Antibody / POLH |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Desoxyribonucleic acid polymerizing enzyme eta (Antibody to) / POLH |
| Alternative technique: |
antibodies |
| Identity: |
9186 |
| Gene: |
POLQ |
More about : POLQ |
| Long gene name: |
DNA polymerase theta |
| Synonyms gene name: |
polymerase (DNA directed), theta polymerase (DNA) theta |
| Synonyms: |
POLH |
| Locus: |
3q13, 33 |
| Discovery year: |
1999-04-15 |
| GenBank acession: |
AF052573 |
| Entrez gene record: |
10721 |
| Pubmed identfication: |
10395804 |
| RefSeq identity: |
NM_199420 |
| Classification: |
DNA polymerases |
| Havana BLAST/BLAT: |
OTTHUMG00000159396 |