| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL2RA |
| Specificity: |
This antibody reacts specifically with IL2RA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse CD25/IL2RA |
| Gene ID: |
16184 |
| Swiss Prot: |
P01590 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternately-spliced IL2RA mRNAs have been isolated, Homodimeric alpha chains (IL2RA) result in low-affinity receptor, Mutations in this gene are associated with interleukin 2 receptor alpha deficiency, Normally an integral-membrane protein, Nov 2009], but the significance of each is presently unknown, constitute the high-affinity IL2 receptor, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis, together with the common gamma chain (IL2RG), while homodimeric beta (IL2RB) chains produce a medium-affinity receptor, The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, [provided by RefSeq |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD25 |
| Also known as: |
IL2RA Polyclonal Antibody |
| Other name: |
Anti-IL2RA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL2RA |
| Short name: |
Anti-IL2RA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, alpha (polyclonal), antibody to-interleukin 2 receptor |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CD25 and IDDM10 and IL2R and p55 and TCGFR, Cell surfaces, IL2RA and IDBG-50566 and ENSG00000134460 and 3559, IL2RA and IDBG-637067 and ENSBTAG00000020892 and 281861, Il2ra and IDBG-136654 and ENSMUSG00000026770 and 16184, alpha, interleukin-2 binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004911 and interleukin-2 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008144 and drug binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019976 and interleukin-2 binding and molecular function this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046013 and regulation of T cell homeostatic proliferation and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process, this GO :0004911 : interleukin-2 receptor activity, this GO :0004911 : interleukin-2 receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0019976 : interleukin-2 binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0019976 : interleukin-2 binding, interleukin 2 receptor |
| Identity: |
6008 |
| Gene: |
IL2RA |
More about : IL2RA |
| Long gene name: |
interleukin 2 receptor subunit alpha |
| Synonyms gene: |
IL2R IDDM10 |
| Synonyms gene name: |
alpha , insulin-dependent diabetes mellitus 10 interleukin 2 receptor |
| Locus: |
10p15, 1 |
| Discovery year: |
1990-01-22 |
| GenBank acession: |
X01057 |
| Entrez gene record: |
3559 |
| Pubmed identfication: |
3925551 17676041 |
| RefSeq identity: |
NM_000417 |
| Classification: |
Sushi domain containing CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000017616 |
| Locus Specific Databases: |
IL2RAbase: Mutation registry for Interleuken 2 receptor &, deficiency LRG_73 , #945 |