| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RGS2 |
| Specificity: |
This antibody reacts specifically with RGS2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cell membrane, Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RGS2 |
| Gene ID: |
5997 |
| Swiss Prot: |
P41220 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds EIF2B5 and blocks its activity, May play a role in leukemogenesis, Plays a role in negative feedback control pathway for adenylyl cyclase signaling, thereby inhibiting the translation of mRNA into protein, Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
RGS2 Polyclonal Antibody |
| Other name: |
Anti-RGS2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RGS2 |
| Short name: |
Anti-RGS2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
24kDa (polyclonal), ALEXA Fluor 594, antibody to-regulator on G-protein signaling 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
24kDa, G0S8, RGS2 and IDBG-105451 and ENSG00000116741 and 5997, RGS2 and IDBG-629676 and ENSBTAG00000034366 and 100848920, Rgs2 and IDBG-197102 and ENSMUSG00000026360 and 19735, beta-tubulin binding, nuclei, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006417 and regulation of translation and biological process this GO :0007049 and cell cycle and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0010614 and negative regulation of cardiac muscle hypertrophy and biological process this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0038032 and termination of G-protein coupled receptor signaling pathway and biological process this GO :0043005 and neuron projection and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0043951 and negative regulation of cAMP-mediated signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0048487 and beta-tubulin binding and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0055119 and relaxation of cardiac muscle and biological process this GO :0060087 and relaxation of vascular smooth muscle and biological process this GO :0060452 and positive regulation of cardiac muscle contraction and biological process this GO :0071877 and regulation of adrenergic receptor signaling pathway and biological process, this GO :0005096 : GTPase activator activity, this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0048487 : beta-tubulin binding, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0048487 : beta-tubulin binding, 513055, regulator of G-protein signaling 2 |
| Identity: |
9998 |
| Gene: |
RGS2 |
More about : RGS2 |
| Long gene name: |
regulator of G-protein signaling 2 |
| Synonyms gene: |
G0S8 |
| Synonyms gene name: |
24kD regulator of G-protein signalling 2, 24kDa , 24kDa regulator of G-protein signaling 2, regulator of G-protein signalling 2 |
| Locus: |
1q31, 2 |
| Discovery year: |
1994-11-01 |
| GenBank acession: |
L13463 |
| Entrez gene record: |
5997 |
| Pubmed identfication: |
8179820 |
| RefSeq identity: |
NM_002923 |
| Classification: |
Endogenous ligands Regulators of G-protein signaling |
| Havana BLAST/BLAT: |
OTTHUMG00000035600 |