| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CIP2A / KIAA1524 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the CIP2A antibody should be determined by the researcher |
| Intented use: |
This CIP2A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8TCG1 |
| Purity: |
Antigen affinity |
| Description: |
CIP2A deficient mice are viable, Importantly, In accordance with the oncogenic role of CIP2A, It is required for the malignant cellular growth and for in vivo tumor formation, More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types, also known as 'cancerous inhibitor of PP2A' and p90, is a protein that in humans is encoded by the KIAA1524 gene, overexpression promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs), suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects, Protein CIP2A |
| Immunogen: |
Amino acids EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH of human KIAA1524 were used as the immunogen for the CIP2A antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CIP2A antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CIP2A / KIAA1524 |
| Short name: |
CIP2A Antibody / KIAA1524 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CIP2A (Antibody to) / KIAA1524 |
| Alternative technique: |
antibodies |
| Identity: |
29302 |
| Gene: |
KIAA1524 |
More about : KIAA1524 |
| Long gene name: |
KIAA1524 |
| Synonyms: |
CIP2A |
| Synonyms name: |
cancerous inhibitor of protein phosphatase 2A |
| Locus: |
3q13, 13 |
| Discovery year: |
2005-01-24 |
| GenBank acession: |
AB040957 |
| Entrez gene record: |
57650 |
| Pubmed identfication: |
10819331 24214971 |
| RefSeq identity: |
NM_020890 |
| Havana BLAST/BLAT: |
OTTHUMG00000159233 |