| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HRPT2 / CDC73 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the HRPT2 antibody should be determined by the researcher |
| Intented use: |
This HRPT2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q6P1J9 |
| Purity: |
Antigen affinity |
| Description: |
And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin, Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, The protein is a component of the the PAF protein complex, This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways, also known as HRPT2, and parathyroid carcinoma, familial isolated hyperparathyroidism, is a protein which in humans is encoded by the CDC73 gene, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex, Cell division cycle 73 |
| Immunogen: |
Amino acids 119-520 of human HRPT2 were used as the immunogen for the HRPT2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HRPT2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HRPT2 / CDC73 |
| Short name: |
HRPT2 Antibody / CDC73 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HRPT2 (Antibody to) / CDC73 |
| Alternative technique: |
antibodies |
| Identity: |
16783 |
| Gene: |
CDC73 |
More about : CDC73 |
| Long gene name: |
cell division cycle 73 |
| Synonyms gene: |
C1orf28 HRPT2 HRPT1 |
| Synonyms gene name: |
Paf1/RNA polymerase II complex component, cerevisiae) hyperparathyroidism 1 , chromosome 1 open reading frame 28 hyperparathyroidism 2 (with jaw tumor) cell division cycle 73, homolog (S |
| Synonyms: |
parafibromin FIHP |
| Synonyms name: |
Paf1/RNA polymerase II complex component |
| Locus: |
1q31, 2 |
| Discovery year: |
2001-10-08 |
| GenBank acession: |
AF312865 |
| Entrez gene record: |
79577 |
| Pubmed identfication: |
11318611 15632063 18755853 |
| RefSeq identity: |
NM_024529 |
| Classification: |
Paf1/RNA polymerase II complex |
| Havana BLAST/BLAT: |
OTTHUMG00000035676 |
| Locus Specific Databases: |
LRG_507 |