| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PLD1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the PLD1 antibody should be determined by the researcher |
| Intented use: |
This PLD1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13393 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties, And PLD1 disrupted association of gamma-secretase protein components, PLD1 is mapped to 3q26, PLD1 regulates intracellular trafficking of beta-amyloid, The enzyme may play a role in signal transduction and subcellular trafficking, This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline, What's more, distinct from its effect on gamma-secretase activity, independent of PLD1catalytic activity, 31, By somatic cell hybrid analysis |
| Immunogen: |
Amino acids 1-330 of human PLD1 were used as the immunogen for the PLD1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PLD1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PLD1 |
| Short name: |
PLD1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphatidylcholine-specific (Antibody to), phospholipase D1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
N-acylphosphatidylethanolamine-specific phospholipase D activity, PLD1 and IDBG-64867 and ENSG00000075651 and 5337, PRKCSH and IDBG-636296 and ENSBTAG00000017490 and 514554, Plasma membranes, Pld1 and IDBG-134603 and ENSMUSG00000027695 and 18805, phosphatidylcholine-specific, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004630 and phospholipase D activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006644 and phospholipid metabolic process and biological process this GO :0006654 and phosphatidic acid biosynthetic process and biological process this GO :0006655 and phosphatidylglycerol biosynthetic process and biological process this GO :0006935 and chemotaxis and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0008152 and metabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016042 and lipid catabolic process and biological process this GO :0031902 and late endosome membrane and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0046474 and glycerophospholipid biosynthetic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0070290 and N-acylphosphatidylethanolamine-specific phospholipase D activity and molecular function, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004630 : phospholipase D activity and also this GO :0005515 : protein binding and also this GO :0035091 : phosphatidylinositol binding and also this GO :0070290 : N-acylphosphatidylethanolamine-specific phospholipase D activity, this GO :0004630 : phospholipase D activity, this GO :0005515 : protein binding, this GO :0035091 : phosphatidylinositol binding, this GO :0070290 : N-acylphosphatidylethanolamine-specific phospholipase D activity, phospholipase D1 |
| Identity: |
9067 |
| Gene: |
PLD1 |
More about : PLD1 |
| Long gene name: |
phospholipase D1 |
| Synonyms gene name: |
phosphatidylcholine-specific , phospholipase D1 |
| Synonyms name: |
choline phosphatase 1 |
| Locus: |
3q26, 31 |
| Discovery year: |
1997-05-29 |
| GenBank acession: |
U38545 |
| Entrez gene record: |
5337 |
| Pubmed identfication: |
9858822 8530346 |
| RefSeq identity: |
NM_002662 |
| Classification: |
Phospholipases Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000156947 |