| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRIM28 / KAP1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the TRIM28 antibody should be determined by the researcher |
| Intented use: |
This TRIM28 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13263 |
| Purity: |
Antigen affinity |
| Description: |
DNA damage repair, Its functionality is dependent upon post-translational modifications, KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator, The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors, The protein localizes to the nucleus and is thought to associate with specific chromatin regions, also known as transcriptional intermediary factor 1b (TIF1b) and KAP1 (KRAB-associated protein-1), and apoptosis, cellular differentiation and proliferation, is a protein that in humans is encoded by the TRIM28 gene, viral suppression, Tripartite motif-containing 28 |
| Immunogen: |
Amino acids 699-835 of human TRIM28 were used as the immunogen for the TRIM28 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRIM28 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Nuclear |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRIM28 / KAP1 |
| Short name: |
TRIM28 Antibody / KAP1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRIM28 (Antibody to) / KAP1 |
| Alternative technique: |
antibodies |
| Identity: |
16384 |
| Gene: |
TRIM28 |
More about : TRIM28 |
| Long gene name: |
tripartite motif containing 28 |
| Synonyms gene name: |
tripartite motif-containing 28 |
| Synonyms: |
TIF1B KAP1 TF1B RNF96 PPP1R157 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 157 |
| Locus: |
19q13, 4 |
| Discovery year: |
2001-08-10 |
| Entrez gene record: |
10155 |
| Pubmed identfication: |
11331580 11226167 |
| RefSeq identity: |
NM_005762 |
| Classification: |
Tripartite motif containing PHD finger proteins Ring finger proteins Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000183546 |