| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IASPP |
| Specificity: |
This antibody reacts specifically with IASPP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IASPP |
| Gene ID: |
10848 |
| Swiss Prot: |
Q8WUF5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also inhibits p53/TP53 function, Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1, and therefore suppressing the subsequent activation of apoptosis, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RAI IASPP |
| Also known as: |
IASPP Polyclonal Antibody |
| Other name: |
Anti-IASPP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IASPP |
| Short name: |
Anti-IASPP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-IASPP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18838 |
| Gene: |
PPP1R13L |
More about : PPP1R13L |
| Long gene name: |
protein phosphatase 1 regulatory subunit 13 like |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 13 like protein phosphatase 1, regulatory subunit 13 like |
| Locus: |
19q13, 32 |
| Discovery year: |
2004-11-26 |
| GenBank acession: |
AF078036 |
| Entrez gene record: |
10848 |
| Pubmed identfication: |
10336463 |
| RefSeq identity: |
NM_006663 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000181784 |