| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SSB |
| Specificity: |
This antibody reacts specifically with SSB |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SSB |
| Gene ID: |
6741 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
5S, 7S, Binds to the 3' termini of virtually all nascent polymerase III transcripts, It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4, It is most probably a transcription termination factor, Sera from patients with systemic lupus erythematosus(SLE) often contain that react with the normal cellular La protein as if this antigen was foreign, The phosphorylation sites are at the C-terminal part of the protein, and 7-2 RNAs, 5S, Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LARP3 La La/SSB |
| Also known as: |
SSB Polyclonal Antibody |
| Other name: |
Anti-SSB Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SSB |
| Short name: |
Anti-SSB (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SSB (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11316 |
| Gene: |
SSB |
More about : SSB |
| Long gene name: |
Sjogren syndrome antigen B |
| Synonyms gene name: |
Sjogren syndrome antigen B (autoantigen La) |
| Synonyms name: |
La ribonucleoprotein domain family, member 3 Lupus La protein La autoantigen |
| Locus: |
2q31, 1 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
6741 |
| Pubmed identfication: |
2468131 1692037 |
| RefSeq identity: |
NM_003142 |
| Classification: |
La ribonucleoprotein domain containing RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132212 |