| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FAK / Focal Adhesion Kinase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the FAK antibody should be determined by the researcher |
| Intented use: |
This FAK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q05397 |
| Purity: |
Antigen affinity |
| Description: |
Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix, Several transcript variants encoding different isoforms have been found for this gene, The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies, This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents, also known as Focal Adhesion Kinase (FAK), but the full-length natures of only three of them have been determined, in humans, is a protein that, is encoded by the PTK2 gene, PTK2 protein tyrosine kinase 2 (PTK2) |
| Immunogen: |
Amino acids AHALAVDAKNLLDVIDQARLKMLGQTRPH of human PTK2/FAK were used as the immunogen for the FAK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FAK antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FAK / Focal Adhesion Kinase |
| Short name: |
FAK Antibody / Focal Adhesion Kinase |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FAK (Antibody to) / Focal Adhesion phosphorylation catalyst |
| Alternative technique: |
antibodies |
| Identity: |
9611 |
| Gene: |
PTK2 |
More about : PTK2 |
| Long gene name: |
protein tyrosine kinase 2 |
| Synonyms gene name: |
PTK2 protein tyrosine kinase 2 |
| Synonyms: |
FAK FADK FAK1 PPP1R71 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 71 |
| Locus: |
8q24, 3 |
| Discovery year: |
1992-10-02 |
| GenBank acession: |
L13616 |
| Entrez gene record: |
5747 |
| Pubmed identfication: |
8422239 |
| RefSeq identity: |
NM_005607 |
| Classification: |
Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000067438 |