| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RAP1A / KREV1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the RAP1A antibody should be determined by the researcher |
| Intented use: |
This RAP1A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P62834 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, Alternative splicing results in multiple transcript variants, And it is activated by several types of guanine nucleotide exchange factors (GEFs), Pseudogenes of this gene have been defined on chromosomes 14 and 17, The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs, The encoded protein undergoes a change in conformational state and activity, This gene encodes a member of the Ras family of small GTPases, and inactivated by two groups of GTPase-activating proteins (GAPs), and may play a role in tumor malignancy, depending on whether it is bound to GTP or GDP, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene |
| Immunogen: |
Amino acids EIFYDLVRQINRKTPVEKKKPKKKSC of human Ras-related protein Rap-1A were used as the immunogen for the RAP1A antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RAP1A antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RAP1A / KREV1 |
| Short name: |
RAP1A Antibody / KREV1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAP1A (Antibody to) / KREV1 |
| Alternative technique: |
antibodies |
| Identity: |
9855 |
| Gene: |
RAP1A |
More about : RAP1A |
| Long gene name: |
RAP1A, member of RAS oncogene family |
| Synonyms: |
KREV-1 SMGP21 |
| Locus: |
1p13, 2 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
BC014086 |
| Entrez gene record: |
5906 |
| Pubmed identfication: |
3143720 |
| RefSeq identity: |
NM_002884 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000011959 |