| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NCoR1 |
| Specificity: |
This antibody reacts specifically with NCoR1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NC0R1 |
| Gene ID: |
9611 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is belongs to the N-CoR nuclear receptor corepressors family, Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, This large complex represses transcription in absence of ligand, Tissue specificity: Ubiquitous, mSin3 and HDACs, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, thus preventing access of the basal transcription, Nuclear co-repressor 2 (N-CoR2) gene (NCOR2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
N-CoR hCIT529I10 TRAC1 hN-CoR KIAA1047 MGC104216 PPP1R109 |
| Also known as: |
NCoR1 Polyclonal Antibody |
| Other name: |
Anti-NCoR1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NCoR1 |
| Short name: |
Anti-NCoR1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NCoR1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7672 |
| Gene: |
NCOR1 |
More about : NCOR1 |
| Long gene name: |
nuclear receptor corepressor 1 |
| Synonyms gene name: |
nuclear receptor co-repressor 1 |
| Synonyms name: |
regulatory subunit 109 , thyroid hormone- and retinoic acid receptor-associated corepressor 1 protein phosphatase 1 |
| Locus: |
17p12-p11, 2 |
| Discovery year: |
1999-12-17 |
| GenBank acession: |
AF044209 |
| Entrez gene record: |
9611 |
| Pubmed identfication: |
7566114 9724795 |
| RefSeq identity: |
NM_006311 |
| Classification: |
Myb/SANT domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000059309 |