| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HINT1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the HINT1 antibody should be determined by the researcher |
| Intented use: |
This HINT1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P49773 |
| Purity: |
Antigen affinity |
| Description: |
AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/b-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells, Several transcript variants, The encoded protein interacts with these substrates via a histidine triad motif, The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, and AMP-NH2, but only one of them protein-coding, have been found for this gene, which is part of the loop that binds to the substrate, Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene |
| Immunogen: |
Amino acids HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK of human HINT1 were used as the immunogen for the HINT1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HINT1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HINT1 |
| Short name: |
HINT1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
histidine triad nucleotide binding protein 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007165 and signal transduction and biological process this GO :0008152 and metabolic process and biological process this GO :0009154 and purine ribonucleotide catabolic process and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process, HINT and NMAN and PKCI-1 and PRKCNH1, HINT1 and IDBG-40323 and ENSG00000169567 and 3094, HINT1 and IDBG-644750 and ENSBTAG00000010959 and 327693, Hint1 and IDBG-174166 and ENSMUSG00000020267 and 15254, hydrolase activity, nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000166 and nucleotide binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0003824 : catalytic activity and also this GO :0005080 : protein kinase C binding and also this GO :0016787 : hydrolase activity, this GO :0003824 : catalytic activity, this GO :0005080 : protein kinase C binding, this GO :0016787 : hydrolase activity, histidine triad nucleotide binding protein 1 |
| Identity: |
4912 |
| Gene: |
HINT1 |
More about : HINT1 |
| Long gene name: |
histidine triad nucleotide binding protein 1 |
| Synonyms gene: |
PRKCNH1 HINT |
| Synonyms gene name: |
histidine triad nucleotide-binding protein |
| Synonyms: |
PKCI-1 |
| Locus: |
5q23, 3 |
| Discovery year: |
1996-05-15 |
| GenBank acession: |
BC007090 |
| Entrez gene record: |
3094 |
| Pubmed identfication: |
8812426 |
| RefSeq identity: |
NM_005340 |
| Havana BLAST/BLAT: |
OTTHUMG00000128995 |