| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FASN / Fatty acid synthase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the FASN antibody should be determined by the researcher |
| Intented use: |
This FASN antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P49327 |
| Purity: |
Antigen affinity |
| Description: |
In some cancer cell lines, Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, The enzyme encoded by this gene is a multifunctional protein, in the presence of NADPH, in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha, into long-chain saturated fatty acids, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene |
| Immunogen: |
Amino acids 1-226 of human FASN were used as the immunogen for the FASN antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FASN antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FASN / Fatty acid synthase |
| Short name: |
FASN Antibody / Fatty acid synthase |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FASN (Antibody to) / Fatty acid synthase |
| Alternative technique: |
antibodies |
| Identity: |
3594 |
| Gene: |
FASN |
More about : FASN |
| Long gene name: |
fatty acid synthase |
| Synonyms: |
FAS SDR27X1 |
| Synonyms name: |
member 1 , short chain dehydrogenase/reductase family 27X |
| Locus: |
17q25, 3 |
| Discovery year: |
1994-05-17 |
| GenBank acession: |
U26644 |
| Entrez gene record: |
2194 |
| Pubmed identfication: |
7835891 7567999 19027726 |
| RefSeq identity: |
NM_004104 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000178527 |