| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IDH2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the IDH2 antibody should be determined by the researcher |
| Intented use: |
This IDH2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P48735 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants, Each NADP(+)-dependent isozyme is a homodimer, Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate, It plays a role in intermediary metabolism and energy production, The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria, These enzymes belong to two distinct subclasses, This protein may tightly associate or interact with the pyruvate dehydrogenase complex, and two NADP(+)-dependent isocitrate dehydrogenases, mitochondrial is an enzyme that in humans is encoded by the IDH2 gene, one of which is mitochondrial and the other predominantly cytosolic, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+), which localize to the mitochondrial matrix, Isocitrate dehydrogenase [NADP] |
| Immunogen: |
Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR of human IDH2 were used as the immunogen for the IDH2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IDH2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IDH2 |
| Short name: |
IDH2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IDH2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5383 |
| Gene: |
IDH2 |
More about : IDH2 |
| Long gene name: |
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial |
| Synonyms gene name: |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| Locus: |
15q26, 1 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
3418 |
| Havana BLAST/BLAT: |
OTTHUMG00000149815 |
| Locus Specific Databases: |
LRG_611 |