| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Progesterone Receptor |
| Specificity: |
This antibody reacts specifically with Progesterone Receptor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human progesterone receptor |
| Gene ID: |
5241 |
| Swiss Prot: |
P06401 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone, Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation, Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation, The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, Progesterone receptor, PR |
| Also known as: |
Progesterone Receptor Antibody |
| Other name: |
Anti-Progesterone Receptor |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Progesterone Receptor |
| Short name: |
Fluor 594, Anti-Progesterone Receptor |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Progesterone Receptor |