| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CTGF |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the CTGF antibody should be determined by the researcher |
| Intented use: |
This CTGF antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29279 |
| Purity: |
Antigen affinity |
| Description: |
And the encoded protein plays a role in chondrocyte proliferation and differentiation, CTGF has important roles in many biological processes, Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis, The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells, also known as CCN2 or connective tissue growth factor, and is critically involved in fibrotic disease and several forms of cancers, and is related to platelet-derived growth factor, and tissue wound repair, angiogenesis, cell adhesion in many cell types, including cell adhesion, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein), migration, proliferation, skeletal development, CTGF |
| Immunogen: |
Amino acids 58-349 of human CTGF were used as the immunogen for the CTGF antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CTGF antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
secreted, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CTGF |
| Short name: |
CTGF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
connective tissue growth factor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCN2 and HCS24 and IGFBP8 and NOV2, CTGF and IDBG-633353 and ENSBTAG00000006367 and 281103, CTGF and IDBG-96631 and ENSG00000118523 and 1490, Ctgf and IDBG-138628 and ENSMUSG00000019997 and 14219, Extracellular, heparin binding, this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0001525 and angiogenesis and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001968 and fibronectin binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005801 and cis- this GO lgi network and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006260 and DNA replication and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009611 and response to wounding and biological process this GO :0009749 and response to glucose and biological process this GO :0010260 and organ senescence and biological process this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016477 and cell migration and biological process this GO :0030154 and cell differentiation and biological process this GO :0030324 and lung development and biological process this GO :0032330 and regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0034059 and response to anoxia and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0043200 and response to amino acid and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050867 and positive regulation of cell activation and biological process this GO :0051385 and response to mineralocorticoid and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0060401 and cytosolic calcium ion transport and biological process this GO :0060452 and positive regulation of cardiac muscle contraction and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0061448 and connective tissue development and biological process this GO :0070278 and extracellular matrix constituent secretion and biological process this GO :0070318 and positive regulation of G0 to G1 transition and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070542 and response to fatty acid and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process, this GO :0001968 : fibronectin binding, this GO :0001968 : fibronectin binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005520 : insulin-like growth factor binding and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005520 : insulin-like growth factor binding, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, connective tissue growth factor |
| Identity: |
2500 |
| Gene: |
CTGF |
More about : CTGF |
| Long gene name: |
connective tissue growth factor |
| Synonyms: |
IGFBP8 CCN2 |
| Locus: |
6q23, 2 |
| Discovery year: |
1992-12-01 |
| GenBank acession: |
X78947 |
| Entrez gene record: |
1490 |
| Pubmed identfication: |
1654338 |
| RefSeq identity: |
NM_001901 |
| Classification: |
CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000015573 |