| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ARSA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the ARSA antibody should be determined by the researcher |
| Intented use: |
This ARSA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P15289 |
| Purity: |
Antigen affinity |
| Description: |
ARSA is mapped to 22q13, Alternatively spliced transcript variants have been described for this gene, Defects in this gene lead to metachromatic leucodystrophy (MLD), In humans, The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate, a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death, arylsulfatase A is encoded by the ARSA gene, namely cerebroside 3-sulfate intocerebroside and sulfate, 33, Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides |
| Immunogen: |
Amino acids QALKQLQLLKAQLDAAVTFGPSQVARGED of human ARSA were used as the immunogen for the ARSA antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ARSA antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ARSA |
| Short name: |
ARSA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ARSA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
713 |
| Gene: |
ARSA |
More about : ARSA |
| Long gene name: |
arylsulfatase A |
| Synonyms name: |
metachromatic leucodystrophy |
| Locus: |
22q13, 33 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X52150 |
| Entrez gene record: |
410 |
| Pubmed identfication: |
15772092 |
| RefSeq identity: |
NM_000487 |
| Classification: |
Sulfatases |
| Havana BLAST/BLAT: |
OTTHUMG00000150180 |