| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Integrin alpha 4 / ITGA4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the Integrin alpha 4 antibody should be determined by the researcher |
| Intented use: |
This Integrin alpha 4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P13612 |
| Purity: |
Antigen affinity |
| Description: |
Alpha 4 chain associates with either beta 1 chain or beta 7 chain, ITGA4 is also mapped to 2q31-q32 by fluorescence in situ hybridization, Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, It makes up half of the alpha4beta1 lymphocyte homing receptor, The product of this gene belongs to the integrin alpha chain family of proteins, This gene encodes an alpha 4 chain, Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage, ITGA4/Integrin alpha4 is an integrin alpha subunit |
| Immunogen: |
Amino acids MWKAGFFKRQYKSILQEENRRDSWSYINS K of human ITGA4 were used as the immunogen for the Integrin alpha 4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Integrin alpha 4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membrane, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Integrin alpha 4 / ITGA4 |
| Short name: |
Integrin alpha 4 Antibody / ITGA4 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a 4 (antigen CD49D, a 4 subunit on VLA-4 receptor), Integrin a 4 (Antibody to) / integrin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD49D and IA4, Cell surfaces, ITGA4 and IDBG-639925 and ENSBTAG00000009256 and 282882, ITGA4 and IDBG-76684 and ENSG00000115232 and 3676, Itga4 and IDBG-183203 and ENSMUSG00000027009 and 16401, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), cell adhesion molecule binding, this GO :0001968 and fibronectin binding and molecular function this GO :0001974 and blood vessel remodeling and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0060324 and face development and biological process this GO :0060710 and chorio-allantoic fusion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072678 and T cell migration and biological process this GO :0090074 and negative regulation of protein homodimerization activity and biological process, this GO :0001968 : fibronectin binding, this GO :0001968 : fibronectin binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, this GO :0050839 : cell adhesion molecule binding, integrin |
| Identity: |
6140 |
| Gene: |
ITGA4 |
More about : ITGA4 |
| Long gene name: |
integrin subunit alpha 4 |
| Synonyms gene: |
CD49D |
| Synonyms gene name: |
alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) , integrin |
| Synonyms: |
CD49d |
| Synonyms name: |
antigen CD49D alpha 4 subunit of VLA-4 receptor |
| Locus: |
2q31, 3 |
| Discovery year: |
1991-08-06 |
| Entrez gene record: |
3676 |
| Pubmed identfication: |
1537388 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000154212 |