| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCL5 / RANTES |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0 |
| Notes: |
Optimal dilution of the CCL5 antibody should be determined by the researcher |
| Intented use: |
This CCL5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P13501 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants that encode different isoforms, Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes, It causes the release of histamine from basophils and activates eosinophils, It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), It is also known as RANTES, The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide, This chemokine, This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells, This gene is one of several chemokine genes clustered on the q-arm of chromosome 17, a member of the CC subfamily, and it suppresses in vitro replication of the R5 strains of HIV-1, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils, which use CCR5 as a coreceptor, Chemokine (C-C motif) ligand 5 is a protein which in humans is encoded by the CCL5 gene |
| Immunogen: |
Amino acids 26-91 of human /CCL5RANTES were used as the immunogen for the CCL5 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCL5 / RANTES |
| Short name: |
CCL5 Antibody / RANTES |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CCL5 (Antibody to) / RANTES |
| Alternative technique: |
antibodies |
| Identity: |
10632 |
| Gene: |
CCL5 |
More about : CCL5 |
| Long gene name: |
C-C motif chemokine ligand 5 |
| Synonyms gene: |
D17S136E SCYA5 |
| Synonyms gene name: |
small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5 |
| Synonyms: |
RANTES SISd TCP228 MGC17164 |
| Synonyms name: |
T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
AF043341 |
| Entrez gene record: |
6352 |
| Pubmed identfication: |
1691736 |
| RefSeq identity: |
NM_002985 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188396 |