| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RALB |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the RALB antibody should be determined by the researcher |
| Intented use: |
This RALB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P11234 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, As a Ras GTPase, In particular, Moreover, Ral proteins have been associated with the progression of several cancers, RalB can be activated by RalGEFs and, RalB functions as a molecular switch that becomes active when bound to GTP and inactive when bound to GDP, RalB is more involved in apoptosis and cell motility, RalB specifically interacts with Exo84 to assemble the beclin-1&ndash, This protein is one of two isoforms of the Ral protein, While the above functions appear to be shared between the two Ral isoforms, activate effectors in signal transduction pathways leading to biological outcomes, and part of the Ras GTPase family, and with Sec5 to activate the innate immune response via the Tank-binding kinase 1 (TBK1), in turn, including bladder cancer and prostate cancer, the other being RalA, their differential subcellular localizations result in their differing involvement in certain biological processes, Ras-related protein Ral-B (RalB) is a protein that in humans is encoded by the RALB gene on chromosome 2, VPS34 autophagy initiation complex |
| Immunogen: |
Amino acids DKVFFDLMREIRTKKMSENKDKNGKKSSKNKKSFKERC of human RALB were used as the immunogen for the RALB antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RALB antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RALB |
| Short name: |
RALB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GTP binding protein) (Antibody to), v-ral simian leukemia viral oncogene homolog B (ras related |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GTP binding, GTP binding protein), Plasma membranes, RALB and IDBG-642536 and ENSBTAG00000032021 and 505238, RALB and IDBG-68212 and ENSG00000144118 and 5899, Ralb and IDBG-187413 and ENSMUSG00000004451 and 64143, this GO :0000910 and cytokinesis and biological process this GO :0001928 and regulation of exocyst assembly and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0030496 and midbody and cellular component this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0060178 and regulation of exocyst localization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, v-ral simian leukemia viral oncogene homolog B (ras related |
| Identity: |
9840 |
| Gene: |
RALB |
More about : RALB |
| Long gene name: |
RAS like proto-oncogene B |
| Synonyms gene name: |
v-ral simian leukemia viral oncogene homolog B |
| Synonyms name: |
ras related GTP binding protein B |
| Locus: |
2q14, 2 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
5899 |
| RefSeq identity: |
NM_002881 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000131435 |