| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
n-Myc / MYCN |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the n-Myc antibody should be determined by the researcher |
| Intented use: |
This n-Myc antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P04198 |
| Purity: |
Antigen affinity |
| Description: |
Amplification of this gene is associated with a variety of tumors, And this protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA, Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene, This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain, also known as m-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene, most notably neuroblastomas, N-myc proto-oncogene protein |
| Immunogen: |
Amino acids EYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC of human MYCN were used as the immunogen for the n-Myc antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the n-Myc antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
n-Myc / MYCN |
| Short name: |
n-Myc Antibody / MYCN |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
n-v-myc myelocytomatosis viral oncogene homolog (avian) (Antibody to) / MYCN |
| Alternative technique: |
antibodies |
| Identity: |
7559 |
| Gene: |
MYCN |
More about : MYCN |
| Long gene name: |
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| Synonyms gene: |
NMYC |
| Synonyms: |
bHLHe37 N-myc MYCNOT |
| Locus: |
2p24, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC002712 |
| Entrez gene record: |
4613 |
| RefSeq identity: |
NM_005378 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000039579 |