| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD44 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CD44 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CD44 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
960 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing is the basis for the structural and functional diversity of this protein, CD44 is a cell-surface glycoprotein involved in cell-cell interactions, It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, This protein participates in a wide variety of cellular functions including lymphocyte activation, Transcripts for its gene undergo complex alternative splicing that results in many functionally distinct isoforms, and matrix metalloproteinases (MMPs), and may be related to tumor metastasis, and tumor metastasis, cell adhesion and migration, collagens, hematopoiesis, however, recirculation and homing, such as osteopontin, the full length nature of some of these variants has not been determined, Cluster of differentiation 44 is also known as LHR or MC56 |
| Immunogen: |
An amino acid sequence from the N-terminus of human CD44 (RFAGVFHVEKNGRYSISRTEAADLCKAF) was used as the immunogen for this CD44 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD44 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD44 |
| Short name: |
CD44 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD44 molecule (Indian blood group) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD44 and IDBG-39556 and ENSG00000026508 and 960, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057, CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, Cell surfaces, hyaluronic acid binding, signal transduction by p53 class mediator and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051216 and cartilage development and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060442 and branching involved in prostate gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070487 and monocyte aggregation and biological process this GO :1900625 and positive regulation of monocyte aggregation and biological process this GO :1902166 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process, this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0002246 and wound healing involved in inflammatory response and biological process this GO :0004415 and hyalurononglucosaminidase activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005540 and hyaluronic acid binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030214 and hyaluronan catabolic process and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043518 and negative regulation of DNA damage response, this GO :0004415 : hyalurononglucosaminidase activity, this GO :0004415 : hyalurononglucosaminidase activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0005540 : hyaluronic acid binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0005540 : hyaluronic acid binding, CD44 molecule (Indian blood group) |
| Identity: |
1681 |
| Gene: |
CD44 |
More about : CD44 |
| Long gene name: |
CD44 molecule (Indian blood group) |
| Synonyms gene: |
MIC4 MDU2 MDU3 |
| Synonyms gene name: |
CD44 antigen (homing function and Indian blood group system) |
| Synonyms: |
IN MC56 Pgp1 CD44R HCELL CSPG8 |
| Synonyms name: |
hematopoietic cell E- and L-selectin ligand chondroitin sulfate proteoglycan 8 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
M59040 |
| Entrez gene record: |
960 |
| Pubmed identfication: |
2454887 |
| RefSeq identity: |
NM_000610 |
| Classification: |
Proteoglycans CD molecules Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000044388 |
| Locus Specific Databases: |
LRG_815 |