| Catalog number: | R31739 |
|---|---|
| Price: | 601 € |
| Supplier: | acr |
| Product name: | SHBG Antibody |
| Quantity: | 0,1 mg |
| Other quantities: | 0.1ml 263€ 1 mililiter 973€ 1000 Tests 337€ 100ug 431€ |
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| Category: | Antibody |
|---|---|
| Concentration: | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | SHBG |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | WB |
| Recommended dilutions: | 5-1ug/ml, Western blot: 0 |
| Notes: | Titration of the SHBG antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: | This SHBG antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: | 6462 |
| Purity: | Antigen affinity |
| Description: | High estrogen, It decreases with high levels of insulin, It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, It has both enhancing and inhibiting hormonal influences, Other sites that produce it include the brain, SHBG is produced mostly by the liver and is released into the bloodstream, and placenta, androgens, andthyroxine cause it to increase, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity, growth hormone, insulin-like growth factor 1 (IGF-1), irrespective of the presence of insulin, prolactin and transcortin, testes, uterus, Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones androgen and estrogen |
| Immunogen: | Human partial recombinant protein (AA 30-210) was used as the immunogen for this SHBG antibody |
| Storage: | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SHBG antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | SHBG |
| Short name: | SHBG Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | SHBG (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 10839 |
| Gene: | SHBG | More about : SHBG |
| Long gene name: | sex hormone binding globulin |
| Synonyms gene name: | sex hormone-binding globulin |
| Synonyms: | ABP TEBG MGC126834 MGC138391 |
| Synonyms name: | androgen binding protein |
| Locus: | 17p13, 1 |
| Discovery year: | 1990-03-14 |
| Entrez gene record: | 6462 |
| Pubmed identfication: | 2587256 |
| RefSeq identity: | NM_001040 |
| Havana BLAST/BLAT: | OTTHUMG00000108153 |
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