| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Nod1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Nod1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Nod1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
10392 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, It is a member of NOD-like receptor protein family and is a close relative of Nod2, It recognizes bacterial molecules and stimulates an immune reaction, Nod1 contains a caspase recruitment domain (CARD), This gene is an intracellular pattern recognition receptor, also known as CARD4, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety, is a protein receptor that in humans is encoded by the NOD1 gene, it has been shown that Nod1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases, which is similar in structure to resistant proteins of plants, Nucleotide-binding oligomerization domain-containing protein 1 |
| Immunogen: |
Human partial recombinant protein (AA 1-160) was used as the immunogen for this Nod1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Nod1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Nod1 |
| Short name: |
Nod1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
nucleotide-binding oli this GO merization domain containing 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16390 |
| Gene: |
NOD1 |
More about : NOD1 |
| Long gene name: |
nucleotide binding oligomerization domain containing 1 |
| Synonyms gene: |
CARD4 |
| Synonyms gene name: |
caspase recruitment domain family, member 4 |
| Synonyms: |
NLRC1 CLR7, 1 |
| Synonyms name: |
CARD domain containing 1 , leucine rich repeat and CARD domain containing 1 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
7p14, 3 |
| Discovery year: |
2001-12-11 |
| GenBank acession: |
AF126484 |
| Entrez gene record: |
10392 |
| Pubmed identfication: |
10224040 10329646 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000023923 |