| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
KCNH2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the KCNH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This KCNH2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3757 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, It is mapped to 7q36, KCNH2 channels show gating properties consistent with many of the outwardly rectifying potassium channels, KCNH2 forms the major portion of one of the ion channel proteins (the 'rapid' delayed rectifier current (IKr)) that conducts potassium (K+) ions out of the muscle cells of the heart (cardiac myocytes), also known as HERG or KV11, and this current is critical in correctly timing the return to the resting state (repolarization) of the cell membrane during the cardiac action potential, but they also have an inactivation mechanism that attenuates efflux during depolarization, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel, 1, 1, KCNH2 |
| Immunogen: |
Human partial recombinant protein (AA 856-1159) was used as the immunogen for this KCNH2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the KCNH2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
KCNH2 |
| Short name: |
KCNH2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KCNH2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6251 |
| Gene: |
KCNH2 |
More about : KCNH2 |
| Long gene name: |
potassium voltage-gated channel subfamily H member 2 |
| Synonyms gene: |
LQT2 |
| Synonyms gene name: |
member 2 , potassium voltage-gated channel, subfamily H (eag-related) |
| Synonyms: |
Kv11, 1 HERG erg1 |
| Locus: |
7q36, 1 |
| Discovery year: |
1993-03-22 |
| GenBank acession: |
U04270 |
| Entrez gene record: |
3757 |
| Pubmed identfication: |
18616963 7842012 8159766 16382104 |
| RefSeq identity: |
NM_000238 |
| Classification: |
Potassium voltage-gated channels |
| Havana BLAST/BLAT: |
OTTHUMG00000158341 |
| Locus Specific Databases: |
Gene Connection for the Heart KCNH2 database at LOVD-China LRG_288 |