| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
KLF6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the KLF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This KLF6 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1316 |
| Purity: |
Antigen affinity |
| Description: |
It is a tumor suppressor gene which is located on 10p15, It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters, The DNA binding and transcriptional activity of this protein, The central region might be involved in activation or posttranslational regulatory pathways, The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements, This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region, and the acidic N-terminal domain might play an important role in the process of transcriptional activation, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes, 1, Kruppel-like factor 6 is a protein that in humans is encoded by the KLF6 gene |
| Immunogen: |
Human partial recombinant protein (AA 38-205) was used as the immunogen for this KLF6 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the KLF6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
KLF6 |
| Short name: |
KLF6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Kruppel-like factor 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BCD1 and CBA1 and COPEB and CPBP and GBF and PAC1 and ST12 and ZF9, DNA-templated and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030183 and B cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function, KLF6 and IDBG-46758 and ENSG00000067082 and 1316, KLF6 and IDBG-639502 and ENSBTAG00000015188 and, Klf6 and IDBG-128907 and ENSMUSG00000000078 and 23849, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0046872 : metal ion binding, this GO :0046872 : metal ion binding, Kruppel-like factor 6 |
| Identity: |
2235 |
| Gene: |
KLF6 |
More about : KLF6 |
| Long gene name: |
Kruppel like factor 6 |
| Synonyms gene: |
BCD1 ST12 COPEB |
| Synonyms gene name: |
core promoter element binding protein |
| Synonyms: |
CPBP GBF Zf9 PAC1 |
| Synonyms name: |
GC-rich binding factor |
| Locus: |
10p15, 2 |
| Discovery year: |
1997-10-16 |
| GenBank acession: |
U51869 |
| Entrez gene record: |
1316 |
| Pubmed identfication: |
9503030 9685731 |
| Classification: |
Kruppel like factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000017567 |