| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FOXO3A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the FOXO3A antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FOXO3A antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
2309 |
| Purity: |
Antigen affinity |
| Description: |
FOXO3A belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain, In addition, In mammals FOXO3A regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span, It is mapped to 6q21, This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, also known as FKHRL1 or FOXO3A, is a human protein encoded by the FOXO3 gene, it is thought that FOXO3A is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD, or downregulation of anti-apoptotic proteins such as FLIP, such as Bim and<, /a>, /search_result, Forkhead box O3, PUMA<, a href=, php?search_txt=puma> |
| Immunogen: |
Human partial recombinant protein (AA 471-673) was used as the immunogen for this FOXO3A antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FOXO3A antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FOXO3A |
| Short name: |
FOXO3A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FOXO3A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3821 |
| Gene: |
FOXO3 |
More about : FOXO3 |
| Long gene name: |
forkhead box O3 |
| Synonyms gene: |
FKHRL1 FOXO3A |
| Synonyms: |
AF6q21 FOXO2 |
| Locus: |
6q21 |
| Discovery year: |
1998-03-23 |
| GenBank acession: |
AF032886 |
| Entrez gene record: |
2309 |
| Pubmed identfication: |
9479491 |
| Classification: |
Forkhead boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000015327 |