| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EDA |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the EDA antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This EDA antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1896 |
| Purity: |
Antigen affinity |
| Description: |
Defects in this gene are a cause of ectodermal dysplasia, It is mapped to Xq13, The encoded protein, The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs, anhidrotic, which belongs to the tumor necrosis factor family, which is also known as X-linked hypohidrotic ectodermal dysplasia, 1, Ectodysplasin-A is a protein that in humans is encoded by the EDA gene |
| Immunogen: |
Human partial recombinant protein (AA 30-391) was used as the immunogen for this EDA antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EDA antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EDA |
| Short name: |
EDA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ectodysplasin A (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ECTD1 and ED1 and ED1-A1 and ED1-A2 and EDA-A1 and EDA-A2 and EDA1 and EDA2 and HED and HED1 and ODT1 and STHAGX1 and XHED and XLHED, EDA and IDBG-636361 and ENSBTAG00000012543 and 616179, EDA and IDBG-74170 and ENSG00000158813 and 1896, Eda and IDBG-161929 and ENSMUSG00000059327 and 13607, Extracellular, protein binding, this GO :0001942 and hair follicle development and biological process this GO :0005102 and receptor binding and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007398 and ectoderm development and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030154 and cell differentiation and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043473 and pigmentation and biological process this GO :0043588 and skin development and biological process this GO :0045177 and apical part of cell and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0060662 and salivary gland cavitation and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061153 and trachea gland development and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, ectodysplasin A |
| Identity: |
3157 |
| Gene: |
EDA |
More about : EDA |
| Long gene name: |
ectodysplasin A |
| Synonyms gene: |
ED1 EDA2 ODT1 |
| Synonyms gene name: |
anhidrotic oligodontia 1 , ectodermal dysplasia 1 |
| Synonyms: |
EDA1 XLHED HED XHED ED1-A1 ED1-A2 EDA-A1 EDA-A2 |
| Locus: |
Xq13, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
U59227 |
| Entrez gene record: |
1896 |
| Pubmed identfication: |
8696334 18657636 16583127 |
| RefSeq identity: |
NM_001399 |
| Classification: |
Tumor necrosis factor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000021764 |
| Locus Specific Databases: |
Mental Retardation database |