| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FHIT |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the FHIT antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FHIT antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
2272 |
| Purity: |
Antigen affinity |
| Description: |
FHIT has been shown to synergize with VHL, Furthermore, In fact, It also acts as a tumor suppressor of HER2/neu driven breast cancer, The gene encompasses the common fragile site FRA3B on chromosome 3p14, This gene, a member of the histidine triad gene family, aberrant transcripts from this gene have been found in about half of all esophageal, also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene, and colon carcinomas, another tumor suppressor, encodes a diadenosine P1, in protecting against chemically - induced lung cancer, stomach, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene, 2, Bis(5'-adenosyl)-triphosphatase, P3-bis(5'-adenosyl)-triphosphate adenylohydrolase involved in purine metabolism |
| Immunogen: |
Human partial recombinant protein (AA 1-147) was used as the immunogen for this FHIT antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FHIT antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FHIT |
| Short name: |
FHIT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FHIT (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3701 |
| Gene: |
FHIT |
More about : FHIT |
| Long gene name: |
fragile histidine triad |
| Synonyms gene name: |
fragile histidine triad gene |
| Synonyms: |
FRA3B AP3Aase |
| Locus: |
3p14, 2 |
| Discovery year: |
1996-10-18 |
| GenBank acession: |
BC032336 |
| Entrez gene record: |
2272 |
| Pubmed identfication: |
8598045 9671749 26181368 |
| RefSeq identity: |
NM_002012 |
| Havana BLAST/BLAT: |
OTTHUMG00000158591 |