| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DRD1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the DRD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DRD1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1812 |
| Purity: |
Antigen affinity |
| Description: |
D1 and D2, D1 receptors can stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases, D1 receptors regulate neuron growth and differentiation, DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity, It is the most highly expressed DA receptor subtype among the DA receptor family, Receptors for dopamine have been classified into two functional types, They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins, also known as DRD1, influence behaviour and modify dopamine D2 receptor-mediated events, is a human gene, Dopamine receptor D1 |
| Immunogen: |
Human partial recombinant protein (AA 249-446) was used as the immunogen for this DRD1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DRD1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DRD1 |
| Short name: |
DRD1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
dopamine receptor D1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DADR and DRD1A, DRD1 and IDBG-58384 and ENSG00000184845 and 1812, DRD1 and IDBG-647825 and ENSBTAG00000047719 and 281125, Drd1a and IDBG-153258 and ENSMUSG00000021478 and 13488, coupled to cyclic nucleotide second messenger and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0007191 and adenylate cyclase-activating dopamine receptor signaling pathway and biological process this GO :0007212 and dopamine receptor signaling pathway and biological process this GO :0007416 and synapse assembly and biological process this GO :0007612 and learning and biological process this GO :0007613 and memory and biological process this GO :0007617 and mating behavior and biological process this GO :0007625 and grooming behavior and biological process this GO :0007626 and locomotory behavior and biological process this GO :0007628 and adult walking behavior and biological process this GO :0007631 and feeding behavior and biological process this GO :0008306 and associative learning and biological process this GO :0008542 and visual learning and biological process this GO :0010579 and positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway and biological process this GO :0014002 and astrocyte development and biological process this GO :0015872 and dopamine transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019226 and transmission of nerve impulse and biological process this GO :0019228 and neuronal action potential and biological process this GO :0021542 and dentate gyrus development and biological process this GO :0021756 and striatum development and biological process this GO :0021766 and hippocampus development and biological process this GO :0021853 and cerebral cortex GABAergic interneuron migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030432 and peristalsis and biological process this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0035106 and operant conditioning and biological process this GO :0035240 and dopamine binding and molecular function this GO :0042053 and regulation of dopamine metabolic process and biological process this GO :0042220 and response to cocaine and biological process this GO :0042311 and vasodilation and biological process this GO :0042417 and dopamine metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042711 and maternal behavior and biological process this GO :0043268 and positive regulation of potassium ion transport and biological process this GO :0046323 and glucose import and biological process this GO :0046959 and habituation and biological process this GO :0046960 and sensitization and biological process this GO :0048148 and behavioral response to cocaine and biological process this GO :0051281 and positive regulation of release of sequestered calcium ion into cytosol and biological process this GO :0051482 and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway and biological process this GO :0051584 and regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0051968 and positive regulation of synaptic transmission, coupled via Gs, coupled via Gs and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004952 : dopamine receptor activity and also this GO :0005515 : protein binding and also this GO :0035240 : dopamine binding, coupled via Gs and molecular function this GO :0001659 and temperature homeostasis and biological process this GO :0001661 and conditioned taste aversion and biological process this GO :0001662 and behavioral fear response and biological process this GO :0001963 and synaptic transmission, dopamine receptor activity, dopaminergic and biological process this GO :0001975 and response to amphetamine and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004952 and dopamine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006606 and protein import into nucleus and biological process this GO :0006936 and muscle contraction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, glutamatergic and biological process this GO :0060134 and prepulse inhibition and biological process this GO :0060158 and phospholipase C-activating dopamine receptor signaling pathway and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0071870 and cellular response to catecholamine stimulus and biological process, nuclei, this GO :0001588 and dopamine receptor activity, this GO :0001588 : dopamine receptor activity, this GO :0001588 : dopamine receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004952 : dopamine receptor activity, this GO :0005515 : protein binding, this GO :0035240 : dopamine binding, dopamine receptor D1 |
| Identity: |
3020 |
| Gene: |
DRD1 |
More about : DRD1 |
| Long gene name: |
dopamine receptor D1 |
| Locus: |
5q35, 2 |
| Discovery year: |
1990-04-27 |
| GenBank acession: |
X55760 |
| Entrez gene record: |
1812 |
| RefSeq identity: |
NM_000794 |
| Classification: |
Dopamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130557 |