| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Desmin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Desmin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This Desmin antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1674 |
| Purity: |
Antigen affinity |
| Description: |
Additionally, DES is a member of the intermediate filament (IF) protein family, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions, It is one of the earliest myogenic markers, It is very important in muscle cell architecture and structure since it connects many components of the cytoplasm, It may be also play an important role in mitochondria function, also called Desmin, and is expressed in satellite stem cells and replicating myoblasts, and this gene is mapped to 2q35, both in heart and somites, is a protein that in humans is encoded by the DES gene, DES |
| Immunogen: |
Human partial recombinant protein (AA 1-304) was used as the immunogen for this Desmin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Desmin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene: |
DES |
More about : DES |
| Gene target: |
Desmin |
| Short name: |
Desmin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Desmin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2770 |
| Long gene name: |
desmin |
| Synonyms: |
CMD1I CSM1 CSM2 |
| Synonyms name: |
intermediate filament protein |
| Locus: |
2q35 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF521879 |
| Entrez gene record: |
1674 |
| Pubmed identfication: |
2673923 9736733 |
| RefSeq identity: |
NM_001927 |
| Classification: |
Intermediate filaments Type III |
| Havana BLAST/BLAT: |
OTTHUMG00000058924 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_380 |