| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CSK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CSK antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CSK antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
1445 |
| Purity: |
Antigen affinity |
| Description: |
CSK suppresses activity of the Src family of protein kinases by phosphorylation of family members at a conserved C-terminal site in Src, CSKs control of the Src family activity is widely thought to be central to regulation of the immune response, It can downregulate tyrosine kinase activity of the Src oncoprotein through tyrosine phosphorylation of the carboxy terminus, It is mapped to 15q24, Since cell transformation by Src oncoproteins is caused by various mechanisms that interfere with this phosphorylation, the gene might function as an antioncogene, 1, CSK is a non-receptor protein tyrosine kinase protein that in humans is encoded by the CSK gene |
| Immunogen: |
Human partial recombinant protein (AA 2-204) was used as the immunogen for this CSK antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CSK antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CSK |
| Short name: |
CSK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CSK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2444 |
| Gene: |
CSK |
More about : CSK |
| Long gene name: |
CSK, non-receptor tyrosine kinase |
| Synonyms gene name: |
c-src tyrosine kinase |
| Locus: |
15q24, 1 |
| Discovery year: |
1992-03-20 |
| Entrez gene record: |
1445 |
| Pubmed identfication: |
1377109 |
| RefSeq identity: |
NM_004383 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000142814 |